Born into a family of musicians, Agnes Sulem began very early the study of music. She studied at the Conservatoire de Nice and then at the Conservatoire National Supérieur de Musique in Paris, where she obtained a 1st Violin Prize and 1st Unanimous Chamber Music Prize. In parallel to her musical background, she conducted high-level scientific studies.

Since its foundation in 1981, Sulem has been the first violin of the Rosamonde Quartet. Winner of several international competitions (Evian 1983, Salzburg 1986), the Rosamonde Quartet has an international career and its discography is rich and varied.

Agnès Sulem has performed as a soloist with various orchestras. She is a professor of chamber music (class of quartets) at the CNSM in Lyon and is regularly invited to give Master classes of quartet.